Osteoporosis in Men

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Wehren L.E. , Hawkes W. , Hebel J.R. Gender differences in mortality after hip fracture. Osteoporosis Int 2000; 11(suppl 2): S151–S152

Orwoll E.S. , Bevan L. , Phipps K.R. Determinants of bone mineral density in older men. Osteoporosis Int 2000; 11: 815–21

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Finkelstein J.S. , Klibanski A. , Neer R.M. A longitudinal evaluation of bone mineral density in adult men with histories of delayed puberty. J Clin Endocrinol Metabol 1996; 81: 1152–5

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Finkelstein J.S. , Klibanski A. , Neer R.M. Comment on normal volumetric bone mineral density and bone turnover in young men with histories of constitutional delay of puberty. J Clin Endocrinol Metabol 1999; 84: 3400a–2a

Finkelstein J.S. , Klibanski A. , Neer R.M. Osteoporosis in men with idiopathic hypogonadotrophic hypogonadism. Ann Intern Med 1987; 106: 354–61

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Crilly R.G. , Anderson C. , Hogan D. , Delaquerriere-Richardson L. Bone histomorphometry, bone mass and related parameters in alcoholic males. Calcif Tissue Int 1988; 43: 269–76

Hills E. , Dunstan C.R. , Wong S.Y. , Evans R.A. Bone histology in young adult osteoporosis. J Clin Pathol 1989; 42: 391–9

Janssen J.A.M.J. , Burger H. , Stolk R.P. Gender-specific relationships between serum free and total IGF-I and bone mineral density in elderly men and women. Europ J Endocrinol 1998; 138: 627–32

Kurland E.S. , Rosen C.J. , Cosman F. Insulin-like growth factor-1 in men with idiopathic osteoporosis. J Clin Endocrinol Metab 1997; 82: 2799–805

Byers R.J. , Hoyland J.A. , Braidman I.P. Osteoporosis in men: a cellular endocrine perspective of an increasingly common clinical problem. J Endocrinol 2001; 168: 353–62

Jackson J.A. , Riggs M.W. , Spiekerman A.M. Testosterone deficiency as a risk factor for hip fractures in men: a case–control study. Am J Med Sci 1992; 304: 4–8

Greendale G.A. , Edelstein S. , Barrett-Connor E. Endogenous sex steroids and bone mineral density in older men and women: the Rancho Bernardo Study. J Bone Miner Res 1997; 12: 1833–43

Center J.R. , Nguyen T.V. , Sambrook P.N. , Eisman J.A. Hormonal and biochemical parameters in the determination of osteoporosis in elderly men. J Clin Endocrinol Metab 1999; 84: 3626–35

Daniell H.W. Osteoporosis after orchiectomy for prostatic cancer. J Urol 1997; 157: 439–45

Slemenda C.W. , Longcope C. , Zhou L. Sex steroids and bone mass in older men. Positive association with serum estrogens and negative association with androgens. J Clin Invest 1997; 100: 1755–9

Nyquist F. , Gardsell P. , Sernbo I. , Jeppsson J.O. , Johnell O. Assessment of sex hormones and bone mineral density in relation to occurrence of fracture in men; a prospective population-based study. Bone 1998; 22: 147–551

Khosla S. , Melton L.J. , Atkinson E.J. Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women; a key role for bioavailable estrogen. J Clin Endocrinol Metabol 1998; 83: 2266–74

Riggs B.L. , Khosla S. , Melton L.J. A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Mineral Res 1998; 13: 763–73

Szulc P. , Munoz F. , Claustrat B. Bioavailable estradiol may be an important determinant of osteoporosis in men: The MINOS study. J Clin Endocrinol Metabol 2001; 86: 192–9

Smith E.P. , Boyd J. , Frank G.R. Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med 1994; 331: 1056–61

Morishima A. , Grumbach M.M. , Simpson E.R. Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of oestrogen. J Clin Endocrinol Metab 1995; 80: 3689–98

Soule G.S. , Conway G. , Prelevic G.M. Osteopenia as a feature of the androgen insensitivity syndrome. Clin Endocrinol 1995; 43: 671–5

Marcus R. , Leary D. , Schneired D.L. The contribution of testosterone to skeletal development and maintenance: lesson from androgen insensitivity syndrome. J Clin Endocrinol Metab 2000; 85: 1032–5

Abu E.O. , Horner A. , Kusec V. , Trifitt J.T. , Compston J.E. The localisation of androgen receptors in human bone. J Clin Endocrinol Metabol 1997; 82: 3493–7

Pederson L. , Kremer M. , Judd J. Androgens regulate bone resorption activity in isolated osteoclasts in vitro. Proc Natl Acad Sci USA 1999; 96: 505–10

Hofbauer L.C. , Khosla S. Androgen effects on bone metabolism: recent progress and controversies. Eur J Endocrinol 1999; 140: 271–86

Gori F. , Hofbauer L.C. , Conover C.A. , Khosla S. Effects of androgens on the insulin-like growth factor system in an androgen-responsive human osteoblastic cell line. Endocrinology 1999; 140: 5579–86

Falahati-Nini A. , Riggs L.B. , Atkinson E.J. Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. J Clin Invest 2000; 106: 1556–60

Behre H.M. , Kliesch S. , Leifke F. Long-term effect of testosterone therapy on bone mineral density in hypogonadal men. J Clin Endocrinol Metab 1997; 82: 2386–90

Finkelstein J.S. , Klibanski A. , Neer R.M. Increases in bone density during treatment of men with idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab 1989; 69: 776–83

Guo C-Y , Jones T.H. , Eastell R. The treatment of isolated hypogonadotropic hypogonadism. Effect on bone mineral density and bone turnover. J Clin Endocrinol Metab 1997; 82: 658–65

Snyder P.J. , Peachey H. , Hannoush P. Effects of testosterone treatment on bone mineral density in men over 65 years of age. J Clin Endocrinol Metab 1999; 84: 1966–71

Anderson F.H. , Francis R.M. , Faulkner K. Androgen supplementation in eugonadal men with osteoporosis–effects of 6 months of treatment on bone mineral density and cardiovascular risk factors. Bone 1966; 18: 171–7

Anderson F.H. , Francis R.M. , Peaston R.T. , Wastell H.J. Androgen supplementation in eugonadal men with osteoporosis–effects of 6 months of treatment on markers of bone formation and resorption. J Bone Miner Res 1997; 12: 472–8

Orwoll E. , Ettinger M. , Weiss S. Alendronate for the treatment of osteoporosis in men. N Engl J Med 2000; 343: 604–10

Kurland E.S. , Cosman F. , McMahon D.J. Parathyroid hormone as a therapy for idiopathic osteoporosis in men: effects on bone mineral density and bone markers. J Clin Endocrinol Metab 2000; 85: 3069–76

Bateman T.A. , Zimmerman R.J. , Ayers R.A. Histomorphometric, physical and mechanical effects of spaceflight and insulin-like growth factor-1 on rat long bones. Bone 1998; 23: 527–35

Cemborain A. , Castilla-Cortazar I. , Garcia M. Osteopenia in rats with liver cirrhosis: beneficial effects of IGF-1 treatment. J Hepatol 1998; 28: 122–31