Diabetes mellitus in the young

Bottazzo GF , Florin-Christensen A , Doniach D. Islet cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies. Lancet 1974; ii: 1279–83

Baekkeskov V , Aanstoot HJ , Christgau S Identification of the 64k autoantigen in insulin-dependent diabetes as the GABA synthesizing enzyme glutamic acid decarboxylase. Nature 1990; 347: 152–6

Verge CF , Howard NJ , Rowley MJ Antiglutamate decarboxylase and other antibodies at the onset of childhood IDDM: a population based study. Diabetologia 1994; 37: 113–20

Ledermann HM. Is maturity onset diabetes at young age (MODY) more common in Europe than previously assumed? Lancet 1995; 345: 648

Winter WE , Nakamura M , House DV. Monogenic diabetes mellitus in youth. The MODY syndromes. Endocrinol Metab Clin NA 1999; 28: 765–85

Yamagata K , Ruruta H , Oda N Mutations in the hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1). Nature 1996; 384: 458

Froguel P , Zoulai H , Vionnet N Familial hyperglycaemia due to mutations in glucokinase: definition of a subtype of diabetes mellitus. N Engl J Med 1993; 328: 676–702

Page RC , Hattersley AT , Levy JC Clinical characteristics of subjects with a missense mutation in glucokinase. Diabet Med 1995; 12: 209–17

Hattersley AT. Maturity-onset diabetes of the young: clinical heterogeneity explained by genetic heterogeneity. Diabet Med 1998; 15: 15–24

Velho G , Blanche H , Vaxillaire M Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families. Diabetologia 1997; 40: 217–24

Appleton M , Ellard S , Bulman M , Frayling T , Page R , Hattersley AT. Clinical characteristics of the HNF1α (MODY3) and glucokinase mutations [Abstract]. Diabetologia 1997; 40: A161

Yamagata K , Oda N , Kaisaki PJ Mutations in the hepatocyte nuclear factor-lα gene in maturity-onset diabetes of the young (MODY3). Nature 1996; 384: 455

Stoffers DA , Zinkin NT , Stanojevic V Pancreatic agenesis attributable to a single nucleotide deletion in the human IPFI gene coding sequence. Nat Genet 1997; 15: 106

Stoffers DA , Ferrer J , Clarke WL , Habener JF. Early-onset type II diabetes mellitus (MODY4) linked to IPFI. Nat Genet 1997; 17: 384

Horikawa Y , Iwasaki N , Hara M Mutation in hepatocyte factor-1β gene (TCF2) associated with MODY. Nat Genet 1997; 17: 384

O'Rahilly S , Spivey RS , Holman RR , Nugent Z Type II diabetes of early onset: a distinct clinical and genetic syndrome? BMJ 1987; 294: 923–8

Doria A , Yang Y , Malecki M , Scotti S , Dreyfus J Phenotypic characteristics of early-onset-autosomal-dominant diabetes unlinked to maturity-onset diabetes of the young (MODY) genes. Diabetes Care 1999; 22: 253–61

Turner R , Stratton I , Horton V (UKPDS 25). Autoantibodies to islet cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes. Lancet 1997; 350: 1288–93

Tuomi T , Groop LC , Zimmet PZ , Rowley MJ Antibodies to glutamic acid decarboxylase reveal latent autoimmune diabetes mellitus in adults with non-insulin dependent onset of disease. Diabetes 1993; 42: 358–62

Groop L , Miettinen A , Groop P-H , Meri S , Koskimies S , Bottazzo GF. Organ-specific autoimmunity and HLA-DR antigens as markers for beta-cell destruction in patients with type II diabetes. Diabetes 1998; 37: 99–103

Groop LC , Bottazzo GF , Doniach D. Islet cell antibodies identify latent type I diabetes in patients aged 35-75 at diagnosis. Diabetes 1986; 35: 237–41

Carlsson Å , Sundkvist G , Groop L , Tuomi T. Insulin and glucagons secretion in patients with slowly progressing autoimmue diabetes (LADA). J Clin Endocrinol Metab 2000; 85: 76–80

Tuomi T , Groop LC , Zimmet PZ , Rowley MJ , Knowles W , Mackay IR. Antibodies to glutamic acid decarboxylase reveal latent autoimmune diabetes mellitus in adults with non-insulin-dependent onset of disease. Diabetes 1993; 42: 359–62

Isomaa B , Almgren P , Henricsson M Chronic complications in patients with slowly progressing autoimmune type 1 diabetes (LADA). Diabetes Care 1999; 22: 1347–53

Maasen JA , Kadowaki T. Maternally inherited diabetes and deafness: a new diabetes subtype. Diabetologia 1996; 39: 375–82

Goto Y , Nonaka I , Horai S. A mutation in the tRNALeu (UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies. Nature 1990; 348: 651–3

Hao H , Bonilla E , Manfredi G , Di Mauro S , Moraes CT. Segregation patterns of a novel mutation in the mitochondrial tRNA glutamic acid gene associated with myopathy and diabetes mellitus. Am J Hum Genet 1995; 56: 1017–25

Vialettes BH , Paquis-Flucklinger V , Pelissier JF Phenotypic expression of diabetes secondary to a T14709C mutation of mitochondrial DNA. Diabetes Care 1997; 20: 1731–7

Oka Y , Katagiri H , Yazaki Y , Murase T , Kabayashi T. Mitochondrial gene mutation in islet cell antibody positive patients who were initially non-insulin-dependent diabetes. Lancet 1993; 342: 527–8

Velho G , Byrne MM , Clement K Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNA (Leu, UUR) gene mutation. Diabetes 1996; 45: 478–87

Maasen JA , van den Ouweland JMW , Thart LM , Lemkes HHPJ. Maternally inherited diabetes and deafness; a diabetic subtype associated with a mutation in mitochondrial DNA. Horm Metab Res 1997; 29: 50–5