Normative triglyceride levels were obtained from eighty-five infants weighing > 1500 g. At least 80% of their nutritional intake was their own mother's breast milk. Triglyceride levels did not correlate with birth weight, gestational age, volume of milk fed, age in days, or use of milk fortifier. The 95th percentile triglyceride value was 2.5 mmol/L. Assuming that breast milk-fed infants have triglyceride in the normal range, the acceptable limit of triglyceride values in very-low-birth-weight infants receiving IV lipids could be revised upward to 2.5 mmol/L.
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References
1.
Nutrition Committee, American Academy of Pediatrics. Use of intravenous fat emulsions in pediatric patients. Pediatrics1981; 68: 738–43.
2.
HaumontDDeckelbaumRJRichelleM. Plasma lipid and plasma lipoprotein concentrations in low-birth-weight infants given parenteral nutrition with twenty or ten percent lipid emulsion. J Pediatr1989; 118: 787–83.
3.
HallbergD. Elimination of exogenous lipids from the blood stream. Acta Physiol Scand1965; 65 (Suppl): 2–22.
4.
BoedimanDMurakamiRNakamuraH. Relationship between plasma triglycerides and a polipoprotein CII in infants during the first year of life. J Pediatr Gastroenterol Nutr1993; 17: 82–6.
5.
Nutrition Committee, Canadian Paediatric Society. Nutrient needs and feeding of premature infants. Can Med Assoc J1995; 152: 1765–85.
6.
BallardJLKazmaierNDriverM. A simplified score for assessment of fetal maturation of newly born infants. J Pediatr1979; 95: 769–74.
7.
LubchencoLOHansmanCBoydE. Interuterine growth in length and head circumference as estimated from live births at gestational aged from 26 to 42 weeks. Pediatrics1966; 37: 403–8.
8.
FomonSJFilerLJThomasLN. Growth and serum chemical values of normal breast-fed infants. Acta Paediatr Scand1970; 202 (Suppl): 2–14.
9.
TsengEPotterSMPiccianoMF. Dietary protein source and plasma lipid profiles of infants. Pediatrics1990; 85: 548–52.
10.
HayesKCPronczukAWoodRA. Modulation of infant formula fat profile alters the low-density lipoprotein/high-density lipoprotein ratio and plasma fatty acid distribution relative to those with breast-feeding. J Pediatr1992; 120: S109–16.
11.
GreerFRMcCormickAKashyapML. Late hypertriglyceridemia in very low-birth-weight infants fed human milk exclusively. J Pediatr1987; 111: 466–9.
12.
KringleROJohnsonGF. Acquisition, management and application of laboratory data. Establishment and use of reference values. In: TietzNW, ed. Textbook of clinical chemistry. Philadelphia, PA: WB Saunders, 1986.
13.
WarehamJAFerlautoJJWellsDH. Hypertri-glyceridemia in infants with bronchopulmonary dysplasia. J Pediatr1989; 114: 458–60.
14.
OngJMSimsoloRBSaffariB. The regulation of lipoprotein lipase gene expression by dexamethasone in isolated rat adipocytes. Endocrinology1992; 130: 2310–6.
15.
HahnPMahlerL. The control of cholesterol metabolism and plasma lipid levels in infant rats. Physiol Res1992; 41: 407–10.