Abstract
A new oral amino acid preparation was given to two groups of patients: group 1, five patients on hemodialysis; and group 2, five patients with chronic renal failure (CRF). In group 1, significant prediet and postdiet changes were: BUN 93 to 37 mg% (p smaller than .01); creatinine 13.0 to 9.7 mg% (p smaller than .001); phosphorus 6.6 to 4.2 mg% (p smaller than .05); uric acid 8.7 to 6.0 mg% (p smaller than .01); CO2 16.3 to 21.3 mEq/L (p smaller than .01); hematocrit 18.0 to 20.8% (p smaller than .05). In group 2: BUN 93 to 66 mg% (p smaller than .05); phosphorus 5.6 to 3.8 mg% (p smaller than .05); hematocrit 27.3 to 30.7% (p smaller than .05). Nitrogen balance was positive in all patients. It is concluded that this oral amino acid mixture is well-tolerated and can be utilized in CRF to attain protein anabolism.
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