Many fatigue-damage criteria are widely employed for rubber isolators and have achieved reasonable success under specific loading environments. However, their accuracy is highly influenced by R ratios (the minimum value divided by the maximum value), which pose significant challenges for fatigue assessment in engineering design. In this article, a potential novel methodology, the effective maximum principal strain
, is proposed for fatigue capacity and fatigue evaluations, independent of R ratios. The core concept is to consider both the maximum principal strain
, and the maximum principal strain range
simultaneously, instead of treating them separately in traditional practice. Both variables should be positive, and fatigue capacity can be related to
The cylindrical dumbbell specimens, the AE2 samples and an industrial antivibration product were used to validate this methodology. The result demonstrated that
was achieved on 30 fatigue cases of the cylindrical dumbbell specimens under both negative and positive R ratios, and
on 52 cases of AE2 samples under positive R ratios. Additionally, the criterion was applied to the industrial isolator MDS, and crack initiation was calculated at 64.3k cycles, whereas a deep crack was observed at 400k cycles. It has been shown that the fatigue capacity
of rubber components is independent of R ratios, which would be beneficial for engineering design in estimating the minimum fatigue life without the need for an extensive fatigue calculation process. The suggested methodology could be easily adopted in industry for engineering design and applications.