The Pediatric Pharmacology Research Unit (PPRU) Network was established to help address a long-standing problem that was a barrier to optimal health and well-being of children: lack of testing in children of drugs used to treat children. The PPRU Network was developed in 1994 to address the industry concern that there was no satisfactory place to test drugs in children, to provide top quality data that would facilitate pediatric labeling, and to demonstrate that this could be done. The network accomplishes these goals by solicited cooperative agreement grants from leading pediatric pharmacology experts. The network's developments, accomplishments to date, and plans for the 21st century are covered.
