The concentrations, in parts-per-billion, of 39 trace elements were measured for each of 139 heroin samples that were known to have come from either Chinese or non-Chinese sources. It was found that after dichotomizing the distribution of the concentration of each element, a statistical model based on a linear combination of only eight elements, each significant at the 20% level of significance, explained as much as 78% of the variation in the probability of a heroin sample being of a Chinese source. This model had a high ability to discriminate between heroin samples from Chinese and non-Chinese sources, with a positive predictive value of 95% and a false positive rate of 15%.
ShineJPIkaRVFordTEMultivariate statistical examination of spatial and temporal patterns of heavy contamination in New Bedford harbor marine sediments. Environ Sci Technol.1995;29:1781–1788.
2.
MassartLKaufmanL.Hierarchical nonheirarchical clustering strategy and application to classification of iron meteorites according to their trace element patterns. Analytic Chem.1982;54:911–917.
3.
NeumannH.Comparison of heroin by capillary gas chromatography in Germany. Forensic Sci Intl.1994;69:7–16.
4.
PerilloBAKleinRFFranzosaESRecent advances by the U.S. Drug Enforcement Administration in drug signature and comparative analysis. Forensic Sci Intl.1994;69:1–6.
5.
ArmitagePBerryG.Statistical Methods in Medical Research.Oxford: Blackwell Scientific Publications; 1994.
