Drug-induced alterations in the immune system include immunosuppression, autoimmunity, and hypersensitivity. This paper focuses mainly on drug-induced autoimmunity. The main drug-induced organ-specific and nonorgan specific autoimmune diseases are described as are the clinical and laboratory features which are important in diagnosis. A number of factors which predispose people to the development of drug-induced autoimmune diseases have been identified, but the precise mechanisms underlying these diseases are unknown.
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