Issues Facing Development of New Innovative Medicines

Abstract

The pharmaceutical industry is facing an unprecedented challenge to restore public confidence in the contribution of pharmaceuticals to health care and the value of new drug innovation. Without this confidence, the very fabric of the pharmaceutical and biotech industries and the future of new drug innovation are at risk. The potential long-term impact on patient welfare is enormous. During the 2005 DIA Annual Conference, a panel discussion was held entitled “Medicines and Healthcare: Rebuilding the Trust, Reshaping the Future.” Several key issues affecting public perception and confidence regarding the development and approval of new therapeutic agents were discussed by the panelists. This article represents a compilation of the major topics and concepts discussed during the session as well as the perspective of the authors.

Keywords

Innovation Drug cost Safety Drug advertising Patient education

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References

Tufts Center for the Study of Drug Development. Tufts CSDD Outlook 2005. Tufts University.

Becker

. Economic viewpoint: new drugs cut costs, and Medicare can help. Bus Week. March 22, 2004.

Center for Drug Evaluation and Research, Food and Drug Administration, U. S. Department of Health. CDER 2004 Report to the Nation, Improving Human Health Through Human Drugs..

Pharmaceutical Research Manufacturers Association. Direct-To-Consumer Advertising Strengthens Our Healthcare System. Pharmaceutical Research Manufacturers Association.

Rosenthal

Berndt

Donohue

Frank

Epstein

. Promotion of prescription drugs to consumers. N Engl J Med. 2002;346:498–505.

Young

Paterniti

Bell

Kravitz

. Do prescription drug advertisements educate the public? The consumer answers. Drug Inf J. 2005;39:25–33.

Manton

. Changes in the prevalence of chronic disability in the United States black and nonblack population above age 65 from 1982 to 1999. Proc Natl Acad Sci USA. 2001;98:6354–6359.