Abstract
Pharmacogenomics is an emerging field in drug development and clinical medicine. The advent of single nucleotide polymorphisms (SNPs) and genetic maps of these markers have made the potential for broad applications of this field possible. Drug development and therapeutic success of a compound may be affected by genetic factors that contribute to safety, efficacy, and economics. Pharmacogenomics has the potential for important applications and contributions to help identify and/or minimize adverse events of therapeutic compounds. Some of this knowledge is being applied currently, and as more genetic contributions to drug safety are identified, the applications will increase. Pharmacogenomics may provide opportunities to improve clinical development outcomes, reduce costs of development, increase efficacy and reduce adverse events for specific patients, and develop diagnostic and/or prognostic tests that impact therapeutic decisions.
Get full access to this article
View all access options for this article.