A heuristic derived from an appeal to Scripture as an epistemological source of data is proposed, from which principles are extracted and interpreted, and integrated with psychological theory and research. It represents an effort to expand the utilization of conceptual integration in the domain of Christian counseling in particular. A key text is drawn from the apostle Paul’s letter to first-century Christians (Philippians 4:5–9) in view of its relevance in treating anxious conditions from a transdiagnostic perspective. The distinction is made between the scriptural use of the construct “anxiety” in the neo-testamentary context and present-day definitions framed in DSM-5 terms. The authors postulate the need to develop a faith-based heart-mindset, entrained and anchored in God—a relational subject and love object—that may provide a believer with intrinsic assurance of God’s peace that “surpasses understanding” and empowers their mindful, metacognitive-executive control system, potentiating an adaptive coping process. This approach draws from CBT, MC, and ACT principles, and resonates with Barlow’s transdiagnostic model in particular. An integrated, emergent dimension is introduced—“perichoretic thirdness”—defined in theological-psychological terms, where reliance on God’s transcending/immanent, coparticipatory presence empowers the metacognitive-executive feedforward control system of a believer in enacting purposive, adaptive responses vs. anxiety.
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