This study sought to determine the frequency and factors influencing Impulsive Control Disorders (ICDs) in prolactinoma patients undergoing treatment with dopamine agonists.
Methods
A cross-sectional study involving a convenience sample of 170 patients diagnosed with prolactinoma and receiving dopamine agonist therapy for at least 6 months. Participants were recruited from a single center.
Results
At least one self-reported ICD symptom was present in 23.5% of patients. The most prevalent ICD symptoms were binge eating (17.7%), hypersexuality (14.7%), and compulsive shopping (11.8%). Correlates of ICD symptoms were male gender, macroprolactinoma, elevated prolactin levels, and a previous mental disease history. The likelihood of ICDs increased with the cumulative dose of dopamine agonist medication and the length of treatment. Moreover, individuals with moderate to severe anxiety and depression had a greater risk for ICD compared to those without these symptoms.
Conclusions
Clinicians should prioritize attention during initial diagnosis and ongoing treatment of patients with prolactinoma to risk factors that may elevate the risk of later development of ICDs.
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