Large lesions in the septal forebrain failed to influence the REM sleep of hooded rats under a number of different conditions. This was true whether the electrical activity of the cortex or the activity of the dorsal and ventral hippocampus were used as criteria to assess REM sleep. The amount of REM sleep of animals with and without lesions was the same under baseline and REM deprivations conditions, and also similar under conditions of different types of environmental noise. The most surprising finding was the persistence of hippocampal theta activity after septal co-agulation. As has been reported previously, REM deprivation causes an appreciable compensatory effect. The values of REM sleep obtained under baseline and deprivation conditions were comparable to that previously obtained in our laboratory.
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