Poor organisational strategy differentiates cognitively impaired and unimpaired HIV-positive adults

Abstract

Many HIV-positive individuals manifest symptoms indicative of central nervous system injury. Frequently, those symptoms include cognitive impairment in domains supported by cortical and/or subcortical processing (e.g., executive functioning). The present study investigated one aspect of executive functioning, namely, organisational strategy (i.e., the strategy a person uses when attempting to complete a complex task efficiently). The Rey Complex Figure Test was administered to a group of HIV-positive individuals (n = 63) and a matched group of HIV-negative individuals (n = 63). Organisational strategy in completing the task was measured using the Rey Complex Figure Organizational Strategy Score system, which is a quantitative capture of the quality of the approach taken to the task. There were no significant between-group differences in Rey Complex Figure Organizational Strategy Scores, but within the HIV-positive group, increased level of overall cognitive impairment was associated with increasingly poor organisational strategy. These findings suggest that assessment of organisational strategy (and, more generally, assessment of executive functioning) in completing complex tasks may be a valuable component of neuropsychological batteries that attempt to describe the degree of cognitive impairment (and, by implication, the extent of functional impairment) experienced by people living with HIV.