ShepardCC. Acid fast bacilli in nasal excretions in leprosy and results of inoculation of mice. Am J Hyg1960; 71: 147–57.
2.
KircheimerWFStorrsEE. Attempts to establish the Armadillo (Dasypus novemcinctus Linn) as a model for the study of leprosy. 1. Report of lepromatoid leprosy in an experimentally infected armadillo. Int J Lepr1971; 39: 693–702.
3.
Clark-CurtissJEJacobsWRDochertyMAMolecular analysis of DNA and construction of genomic libraries of Mycobacterium leprae. J Bacteriol1985; 161: 1093–102.
4.
SatishMEssnerRETholeJERClark-CurtissJE. Identification and characterisation of antigenic determinants of Mycobacterium leprae that react with antibodies in sera of leprosy patients. Infect Immun1990; 58: 1327–36.
5.
WilliamsDLGillisTPPortaelsF.Geographically distinct isolates of Mycobacterium leprae exhibit no genotypic diversity by restriction fragment-length polymorphism analysis. Molecular Microbiology1990; 4: 1653–9.
6.
EisensteinBI. The polymerase chain reaction. N Engl J Med1990; 322: 178–83.
7.
HartskeerlRADe WitMYLKlatserPR. Polymerase chain reaction for the detection of Mycobacterium leprae. J Gen Microbiol1989; 135: 2357–64.
8.
GrangeJM. Mycobacteria and human disease.London: Edward Arnold, 1988.
9.
ChakrabartyAKMaireMALamberrPH. SDS Page analysis of M. leprae protein antigens reacting with antibodies from sera from lepromatous patients and infected armadillos. Clin Exp Immunol1982; 49: 523–31.
10.
EngersHDAbeMBloomBRResults of a World Health Organisation sponsored workshop on monoclonal antibodies to Mycobacterium leprae. Infect Immun1985; 48: 603–605.
HartskeerlRAvan RensRMStabelLFEMSelection and characterisation of recombinant clones that produce Mycobacterium leprae antigens recognised by antibodies in sera from household contacts of leprosy patients. Infect Immun1990; 58: 281–2.
13.
YoungBDLathigraRHendrixRStress proteins are immune targets in leprosy and tuberculosis. Proc Natl Acad Sci USA1988; 85: 4267–70.
14.
ShinnickTMVodkinMHWilliamsJC. The Mycobacterium tuberculosis 65-kilodalton antigen is a heat shock protein which corresponds to common antigen and to the Escherichia coli GroEL protein. Infect Immun1988; 56: 446–51.
15.
ShinnickTMSweetserDTholeJThe etiologic agents of leprosy and tuberculosis share an immunoreactive protein antigen with the vaccine strain Mycobacterium bovis BCG. Infect Immun1987; 55: 1932–5.
16.
GonzalezNMDe VriesRRPHLA linked control of predisposition to lepromatous leprosy. J Infect Dis1985; 151: 9–17.
17.
SchurrEMorganKGrosPGenetics of leprosy. Am J Trop Med Hyg1991; 44(Suppl):4–11.
18.
van VoorhisWCKaplanGSarnoENThe cutaneous infiltrates of leprosy; cellular characterisation and the predominant T cell phenotype. N Engl J Med1982; 307: 1593–7.
19.
MehraVBrennanPJRadaELymphocyte suppression in leprosy induced by unique M. leprae glycolipid. Nature1984; 308: 194–6.
20.
YoungDB. What's next in basic research?Int J Lepr1991;59:95–101.
BirdiTJAntiaNH. The macrophage in leprosy: A review on the current status. Int J Lepr1989; 57: 511–25.
24.
YoungDB. Detection of mycobacterial lipids in skin biopsies from leprosy patients. Int J Lepr1981; 49: 198–204.
25.
BrettSJDraperPPayneSNReesRJW. Serological activity of a characteristic phenolic glycolipid from Mycobacterium leprae in sera from patients with leprosy and tuberculosis. Clin Exp Immunol1983; 52: 271–9.
26.
ChoS-NYanagiharaDIHunterSWSerological specificity of phenolic glycolipid 1 from Mycobacterium leprae and use in serodiagnosis of leprosy. Infect Immun1983; 41: 1077–83.
27.
ChoS-NHunterSWGelberRHReaTHBrennanPJ. Quantitation of the phenolic glycolipid of Mycobacterium leprae and relevance to glycolipid antigenemia in leprosy. J Infect Dis1986; 153: 560–9.
28.
YoungDBDissanayakeSMillerRAHumans respond predominantly with IgM immunoglobulin to the species specific glycolipid of Mycobacterium leprae. J Infect Dis1984; 149: 870–3.
29.
FinePEMPonnighausJMBurgessPSeroepidemiological studies of leprosy in northern Malawi based on an enzyme-linked immunosorbent assay using synthetic glycoconjugate antigen. Int J Lepr1988; 56: 243–54.
30.
GroenenGPattynSRGhysPA longitudinal study of the incidence of leprosy in a hyperendemic area in Zaire, with special reference to PGL-antibody results. Int J Lepr1990; 58: 641–50.
31.
EllardG.The chemotherapy of leprosy, part 1. Int J Lepr1990; 58: 704–16.
32.
WHO Technical Report Series, 675. (Chemotherapy of leprosy for control programmes: report of a WHO study group.)Geneva: World Health Organization, 1982.
33.
NoordeenSK. A look at world leprosy. Lepr Rev1991; 62: 72–86.
34.
PetitJHReesRJW. Sulphone resistance in leprosy. An experimental and clinical study. Lancet1984; ii: 673–74.
35.
JiB-H.Drug resistance in leprosy — a review. Lepr Rev1985; 56: 265–78.
36.
EllardGA. The Chemotherapy of leprosy. Part 2. Int J Lepr1991; 59: 82–94.
37.
GrossetJ.Recent developments in the field of multidrug therapy and future research in chemotherapy. Lepr Rev1986; 57(Suppl):223–34.
38.
HastingsRC. Growth of Sulphone resistant M. leprae in the footpad of mice fed dapsone. Proc Soc Exp Bio Med1977; 156: 544–5.
39.
LevyLShepardCCFasalP.The bactericidal effect of rifampicin on M. leprae in man: (a) Single doses of 600, 900, and 1200 mg; (b) daily doses of 300 mg. Int J Lepr1976; 44: 183–7.
WheelerPRRatledgeC.Metabolism in Mycobacterium leprae, Mycobacterium tuberculosis and other pathogenic mycobacteria in tuberculosis and leprosy. Br Med Bull1988; 44: 547–62.
42.
HallRMRatledgeC.Exochelin mediated iron acquisition by the leprosy bacillus. J Gen Microbiol1987; 133: 193–9.
43.
GrossetJHJiBGuelpa-LaurasCCPeraniEGN'DeliL.Clinical trial of Pefloxacin and ofloxain in the treatment of lepromatous leprosy. Int J Lepr1990; 58: 281–95.
44.
FranzblauSGHastingsRC. In vitro and in vivo activities of macrolides against Mycobacterium leprae. Antimicrob Agents Chemother1988; 32: 1758–62.
45.
JiBGrossetJH. Recent advances in the chemotherapy of leprosy. Lepr Rev1990; 61: 313–29.
46.
KatochVMKatochKBaggaA.Immunotherapeutic trials using BCG and Mycobacterium strain w along with MDT in highly bacillated BL/LL cases. Oral Presentation VIth Santa Margherita Ligure meeting October 1990.
47.
KaplanGSarnoENJobCKCellular responses to the intradermal injection of recombinant human gamma interferon in lepromatous leprosy patients. Am J Pathol1987; 128: 345–53.
48.
KaplanGKiesslingRTeklemariamSThe reconstitution of cell-mediated immunity in the cutaneous lesions of lepromatous leprosy by recombinant interleukin 2. J Exp Med1989; 169: 893–907.
Editorial. Vaccines against leprosy. Lancet1987; ii: 83.
51.
ConvitJAranzazuNPinardiMEUlrichM.Immunological changes observed in indeterminate and lepromatous leprosy patients and Mitsuda — ve contacts after innoculation of a mixture of Mycobacterium leprae and BCG. Clin Exp Immunol1979; 36: 214–20.
52.
ConvitJUlrichMAranzazuNCastellanosPLPinardiMEReyesO.The development of a vaccination model using two microorganisms and its application in leprosy and leshmaniasis. Lepr Rev1986; 57: 263–73.
53.
FinePPonnighausJM. Background design and prospects of the Karonga Prevention Trial (KPT), a leprosy vaccine trial in northern Malawi. Trans R Soc Med Hyg (in press).
54.
ChaturvediRMChirmuleNBYellapurkarMVShaikhSVDeoMG. Effects of ICRC antileprosy vaccine in healthy subjects. Int J Lepr1987; 55: 657–66.
55.
TalwarGP. Vaccine based on Mycobacterium w. bacillus. Working paper presented at ‘vaccines’ workshop prior to XIII International Leprosy Congress, The Hague, The Netherlands, 1988.
56.
WatsonJD. Prospects for new generation vaccines for leprosy: Progress, barriers and future strategies. Int J Lepr1989; 57: 834–43.
57.
SinghNBLoweCareReesRJWColstonMJ. Vaccination of mice against M. leprae infection. Infect Immun1989; 57: 653–5.
58.
GelberRHBrennanPJHunterSWEffective vaccination of mice against leprosy bacilli with subunits of Mycobacterium leprae. Infect Immun1990; 58: 711–18.
59.
LambFIKingstonAEEstrada-GIColstonMJ. Heterologous expression of the 65 kilo-dalton antigen of Mycobacterium leprae and murine T-cell responses to the gene product. Infect Immun1988; 56: 653–55.
60.
StoverCKde la CruzVFFuerstTRNew use of BCG for recombinant vaccination. Nature1991; 351: 456–60.
61.
AldoviniAYoungRA. Humoral and cell mediated immune responses to live recombinant BCG-HIV vaccines. Nature1991; 351: 479–82.