Trichosporon asahii is an opportunistic yeast that colonizes the skin and mucous membranes but may cause severe invasive infections in critically ill patients. We report the case of an 81-year old man with extensive second- and third degree thermal burns (30–39% total body surface area) who, during the third week of intensive care, developed a deep infection of a previously amputated femoral stump. Cultures repeatedly yielded multidrug-resistant Pseudomonas aeruginosa and T. asahii, identified by MALDI-TOF mass spectrometry. Combined surgical management and antimicrobial therapy with meropenem and posaconazole led to clinical resolution and a favourable outcome.
Tamayo LomasLDomínguez-Gil GonzálezMMartín LuengoAI, et al.Nosocomial infection due to Trichosporon asahii in a critical burned patient. Rev Iberoam Micol2015; 32: 257–260.
3.
Nobrega de AlmeidaJFranciscoECHolguín RuizA, et al.Epidemiology, clinical aspects, outcomes and prognostic factors associated with Trichosporon fungaemia: results of an international multicentre study carried out at 23 medical centres. J Antimicrob Chemother2021; 76: 1907–1915.
4.
SharmaSBajajDSharmaP. Fungal infection in thermal burns: a prospective study in a tertiary care centre. J Clin Diagn Res2016; 10: PC05–PC07.
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ChenSCPerfectJColomboAL, et al.Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM. Lancet Infect Dis2021; 21: e375–e386.
