Melioidosis presenting as hepatosplenic abscesses: A case series

Abstract

Melioidosis, caused by Burkholderia pseudomallei, is an under-recognised tropical infection that often produces visceral abscesses. Hepatosplenic involvement is less commonly described and can mimic pyogenic or tubercular disease and commonly affects patients with diabetes, alcohol use, or immuno-compromised conditions. We report a retrospective series of 10 culture-confirmed patients from a tertiary care centre in India presenting with liver or splenic abscesses diagnosed by imaging and culture. Treatment comprised intravenous meropenem or ceftazidime followed by oral trimethoprim–sulfamethoxazole. Close follow-up is essential to ensure eradication and reduce relapse.