Herpes simplex virus (HSV) infection of the gastro-intestinal tract is rare, except for the oesophagus, found in immunosuppressed individuals. HSV colitis may also occur, especially in patients with inflammatory bowel disease receiving systemic steroids and antimetabolites. Involvement of the small intestine by HSV is extremely rare. We present a case of dual ileal infection (HSV-1 and Tubercular ileitis) in a 30-year-old immunocompromised individual.
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