Metanephric adenoma is a rare benign mass that may be radiologically indistinguishable from renal cell carcinoma. The clinical presentation of this entity is similar to a malignant renal mass. Only 200 cases have been reported worldwide till now. Furthermore, there are no strongly predictive clinical and radiological criteria. It, therefore, poses a diagnostic challenge. Since post-operative therapy may vary significantly if the lesion turns out to be malignant, it is crucial to distinguish it from other malignant renal masses.
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AzabdaftariGAlroyJBannerBF,et al.S100 protein expression distinguishes metanephric adenomas from other renal neoplasms. Pathol – Res Pract2008; 204: 719–723.
