Hepatitis B virus infection is a global problem and causes several liver diseases including acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Though uncommon, some immune mediated extra-hepatic manifestations may develop during the infection. Exudative ascites during HBV infection is one such.
Hoofnagle. Reactivation of hepatitis B. Hepatology2009; 49: S156–S165.
2.
KappusMRSterlingRK. Extrahepatic manifestations of acute hepatitis B virus infection. Gastroenterol Hepatol (N Y)2013; 9: 123–126.
3.
AbbasAK. Pathologic basis of disease. 7th ed. Philadelphia: W.B. Saunders; 2004. Diseases of immunity. In: Kumar V, Abbas AK, Fausto N, editors; pp. 193–267.
4.
CalvetXBruixJBoschJ, et al. Portal pressure in patients with exudative ascites in the course of acute hepatitis B. Liver1991; 11: 206–210.
5.
ViolaCVinetaLBoschJ, et al.Exudative ascites in the course of acute type B hepatitis. Hepatology1983; 3: 1013–1015.
6.
VallaDFlejouJFLebrecD, et al.Portal hypertension and ascites in acute hepatitis: clinical, hemodynamic and histological correlations. Hepatology1989; 10: 482–487.
7.
OwenRLShapiroH. Pleural effusion, rash and anergy in icteric hepatitis (letter). N Engl J Med 1974; 291: 963–963.
8.
GrossPAGerdingDN. Pleural effusion associated with viral hepatitis. Gastoenterology.1971; 60: 898–902.
9.
QinCZhouLHuZ, et al.Dysregulation of immune response in patients with COVID-19 in Wuhan, China. Clin Infect Dis2020; 15: 762–768.
10.
LvXHYangJLDengK. Clinical outcomes of COVID-19 patients with chronic hepatitis B virus infection still need to be explored. Clin Gastroenterol Hepatol2020; 18: 3055–3056.
11.
LiuRZhaoLChengX, et al.Clinical characteristics of COVID-19 patients with hepatitis B virus infection - a retrospective study. Liver Int2021; 41: 720–730.
12.
Rodríguez-TajesSMiralpeixACostaJ, et al.Low risk of hepatitis b reactivation in patients with severe COVID-19 who receive immunosuppressive therapy. J Viral Hepat2021; 28: 89–94.
