Streptococcus pneumoniae infections continue to be an important cause of morbidity and mortality in low-and middle-income countries. Differentiating S. pneumoniae from viridans group streptococci is essential to ensure appropriate antibiotic therapy. Conventional microbial identification tests can often misidentify the two groups. We used a common pneumococcal urinary antigen test to identify S. pneumoniae that were misidentified by the VITEK 2. The performance of the test was similar to the pneumococcal latex agglutination test.
IkryannikovaLNFilimonovaAVMalakhovaMV, et al.Discrimination between Streptococcus pneumoniae and Streptococcus mitis based on sorting of their MALDI mass spectra. Clin Microbiol Infect2013; 19: 1066–1071.
2.
TelesCSmithARamageG, et al.Identification of clinically relevant viridans group streptococci by phenotypic and genotypic analysis. Eur J Clin Microbiol Infect Dis2011; 30: 243–250.
3.
BartlettJG. Diagnostic tests for agents of community-acquired pneumonia. Clin Infect Dis2011; 52: s296–304.
4.
LigozziMBerniniCBonoraMG, et al.Evaluation of the VITEK 2 system for identification and antimicrobial susceptibility testing of medically relevant gram-positive cocci. J Clin Microbiol2002; 40: 1681–1686.
5.
ChandlerLJReisnerBSWoodsGL, et al.Comparison of four methods for identifying Streptococcus pneumoniae. Diagn Microbiol Infect Dis2000; 37: 285–287.
6.
InningsAKrabbeMUllbergM, et al.Identification of 43 Streptococcus species by pyrosequencing analysis of the rnpB gene. J Clin Microbiol2005; 43: 5983–5991.
7.
DominguezJGaliNBlancoS, et al.Detection of Streptococcus pneumoniae antigen by a rapid immunochromatographic assay in urine samples. Chest2001; 119: 243–249.
8.
SelickmanJPaxosMFileTM, et al.Performance measure of urinary antigen in patients with Streptococcus pneumoniae bacteremia. Diagn Microbiol Infect Dis2010; 67: 129–133.
9.
AdegbolaRAObaroSKBineyE, et al.Evaluation of Binax now Streptococcus pneumoniae urinary antigen test in children in a community with a high carriage rate of pneumococcus. Pediatr Infect Dis J2001; 20: 718–719.
