Scrub typhus is an emerging infectious disease in India. Among its protean clinical manifestations, central nervous system involvement is common. In this prospective observational study, altered sensorium, headache, seizures and aseptic meningitis were found to be common central nervous system manifestations. Prompt treatment with doxycycline reduces morbidity and mortality.
Chrispal A, Boorugu H, Gopinath KG, et al. Scrub typhus: an unrecognized threat in South India – clinical profile and predictors of mortality. Trop Doct 2010; 40: 129–133. Epub 2010 Apr 1.
2.
BleckTP. Central nervous system involvement in rickettsial diseases. Neurol Clin1999; 17: 801–812.
3.
Kim JH, Lee SA, Ahn TB, et al. Polyneuropathy and cerebral infarction complicating scrub typhus. J Clin Neurol 2008; 4: 36–39. doi: 10.3988/jcn.2008.4.1.36. Epub 2008 Mar 20.
4.
Lee KL, Lee JK, Yim YM, Lim OK and Bae KH. Acute transverse myelitis associated with scrub typhus: case report and a review of literatures. Diagn Microbiol Infect Dis 2008; 60: 237–239. Epub 2007 Nov 7.
5.
MahajanSKRolainJMKangaARaoultD. Scrub typhus involving central nervous system, India, 2004–2006. Emerg Infect Dis2010; 16: 1641–1643.
