Prevalence of hepatitis C and B virus among patients infected with HIV: a cross-sectional analysis of a large HIV care programme in Myanmar

Abstract

Co-infection with the hepatitis C virus (HCV) and/or hepatitis B virus (HBV) influences the morbidity and mortality of patients with HIV. A cross sectional analysis was of 11,032 HIV-infected patients enrolled in the Integrated HIV Care Program from May 2005 to April 2012 and Epi-info 3.5 was used to determine the serological prevalence of chronic hepatitis B and hepatitis C. The mean ± standard deviation age of patients was 36 ± 8.4 years (adult cohort) and 7 ± 3 years (paediatric cohort). The sero prevalence of hepatitis B surface antigen, hepatitis C (anti HCV antibodies) and triple infection are 8.7%, 5.3% and 0.35%, respectively. Men who have sex with men are at the highest risk of being co-infected with hepatitis B while intravenous drug users are at the highest risk of being co-infected with hepatitis C. It is important to screen for hepatitis B and C in HIV infected people in order to provide quality care for HIV patients with co-infection.

Keywords

HIV hepatitis prevalence co-infection mode of transmission

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References

Weber

Sabin

Friis-Moller

. Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study. Arch Intern Med 2006; 166: 1632–1641.

Koziel

Peters

. Viral hepatitis in HIV infection. N Engl J Med 2007; 356: 1445–1454.

Alter

. Epidemiology of viral hepatitis and HIV co-infection. J Hepatol 2006; 44(1 Suppl): S6–S9.

Sulkowski

. Viral hepatitis and HIV coinfection. J Hepatol 2008 Feb; 48(2): 353–367.

Thio

. Hepatitis B in the human immunodeficiency virus-infected patient: epidemiology, natural history, and treatment. Semin Liver Dis 2003; 23: 125–136.

Shen Y, Wang Z, Qi T, et al. Serological survey of viral hepatitis markers among newly diagnosed patients with HIV/AIDS in China. HIV Med 2012; doi:10.1111/j.1468-1293.2012.01048. Epub 2012, Sept 24.

Lwin

Shinji

Khin

. Hepatitis C virus genotype distribution in Myanmar: Predominance of genotype 6 and existence of new genotype 6 subtype. Hepatol Res 2007; 37: 337–345.

Myo

San

. Prevalence and factors associated with hepatitis C virus infection among Myanmar blood donors. Acta Med Okayama 2010; 64: 317–321.

Sa-Nguanmoo

Tangkijvanich

Thawornsuk

. Molecular epidemiological study of hepatitis B virus among migrant workers from Cambodia, Laos and Myanmar to Thailand. J Med Virol 2010; 82: 1341–1349.

10.

Zhou

Liu

Yao

. Comparison of HIV-, HBV-, HCV- and co-infection prevalence between Chinese and Burmese intravenous drug users of the China‐Myanmar border region. PLoS One 2011; 6: e16349–e16349.