The formation of mixed disulfide in the reaction of thioglycollic acid with pure cystine and also with cystine residues in wool has been investigated quantitatively. The set obtained by wool treated with thioglycollic acid under various conditions has been compared with the amounts of mixed disulfide formed under these conditions and conclusions derived.
Ampola, M., Bixby, E.M., Crawhall, J.C., Efron, M.L., and Parker, R., Isolation of New Sulphur Containing Amino Adds. Biochem. J.107, 16 (1968) .
2.
Asquith, R.S. and Garcia-Dominguez , J.J., New Amino Acids in Alkali-Treated Wool, J. Soc. Dyers Colourists84, 155-158 (1968).
3.
Atfield, G.N. and Morris, C.J.O.R., Analytical Separations by High Voltage Electrophoresis, Biochem. J.81, 606-614 (1961).
4.
Baltrop, J.A. , Hayes, P.M., and Calvin, M., The Chemistry of 1,2 Dithiolane (Trimethylene disulfide) as a Model for Primary Quantum Conversion Act in Photosyn, J. Amer. Chem. Soc.76, 4348-4367 (1954 ).
5.
Bersin T. and Studel, Polarimetric Investigation of Thiodisulfide System, Ber. 71B, 1015-1024 (1938).
6.
Crewther, W.G. , Thiol-Disulfide Interchange Reactions in the Setting of Single Wool Fibers, J. Soc. Dyers Colourists82, 54-58 (1966).
7.
C.S.I.R.O. Wool Research Laboratories, Amino Add Composition of Wool and Main Wool Protein Fractions, Annual Report, 196H7, pp. 20-21.
8.
Eldjarn, L. and Phil.A., Interaction Between Biologically Important Thiols and Disulfides. J. Biol. Chem.225, 499-510 (1957).
9.
Footner, H.B. and Smiles, S., Reactions of Organic Thiosulfates. J. Chem. Soc.127, 2887 (1925).
10.
Hamilton, P.B. , Ion-Exchange Chromatography of Amino Acids: A Single Column High-Resolving Fully Automatic Procedure, Anal. Chem.35, 2055-2064 (1963).
11.
Heilmann, J., Barrollier, J., and Watzke, E., Polychrome Development of Amino Acids on Paper-Chromatograms and Electrophoretograms , Z. Physiol. Chem.309, 219-220 (1957).
12.
Kolthoff, I.M. , Stricks, W., and Kapoor, R.C., Equilibrium Constants of Exchange Reactions of Cystine with Glutathione and with Thioglycollic Acid both in Oxidized and Reduced State. J. Amer. Chem. Soc.77, 4733-4739 (1955).
13.
Lamfrom, H. and Nielsen, S.O., Mercaptolysis of Cystine— Synthesis of an Asymmetric Disulfide-Containing Half Cystine, Compt. rend. trav. Lab. Carliberg.30, 360-362 (1958).
14.
Manakta, H. and Niinami, Studies on Setting of Wool, J. Soc. Textile Cell. Ind. Japan19, 392-400 (1963).
15.
Milligan, B. and Swan, J.M., SomeDyes Solubilized by Thiosulfate Groups, Textile Res. J.31, 18-25 (1961).
16.
Milligan, B. , Caldwell, J.B., and Leach, S.J., The Role of Thiol Groups in Setting and Release of Set, Third Intern. Wool Textile Res. Conf. Section2, 309-314 (1965).
17.
Osterloh, F. , Das Verhalten Von Farbstoffen mit Thiosulfat-Gruppenbeim Farben von Wolle, Melliand Textile ber.44, 57-62 (1963).
18.
Patterson, W.I., Geiger, W.B., Mizel, L.R., and Harris, M.,. Role of Cystine in the Structure of Fibrous Protein, Wool, J. Res. Nat. Bur. Stds. 27, 89-103 (1941).
Sanger, F., Ryle, A.B., Smith, L.F., and Kitai, R., The Distribution of Cystine Residues in Insulin, Proc. Intern. Textile Res. Conf. Section 1, C49-C61 (1955).
21.
Savige, W.E. , The Dispersion of Wool Protein by Thiols in Acid Solutions, Textile Res. J.30, 1-10 (1960) .
22.
Schoberl, A. and Tausent, A., Reactivity of the Disulfide Bonds in Wool and Hair: Synthesis and Properties of Unsymmetric Disulfide Dicarboxylic Acids, Proc. Intern. Textile Res. Conf. Australia, Section 1, C-150-C-156 ( 1955).
23.
Schoberl, A. , New Reactions in Reduced Wool Fibers. J. Textile Institute51, T613-T627 ( 1960).
24.
Speakman, J.B. and Whewell, C.S., The Reactivity of Sulfur Linkage in Animal Fibers, J. Soc. Dyers Colourists52, 335-346 (1936).
25.
Swan, J.M., Thiols, Disulfides,' and Thiosulfates: Some New Reactions and Possibilities in Peptide and Protein Chemistry, Nature180, 643-645 (1957).
26.
Zahn, H. and Gerthsen, T., Methods for Detection of Siroset Treatment in Wool Fabrics, J. Soc. Dyers Colourists75, 604-605 (1959).
