PKDEMO - A Pharmacokinetic Demonstration simulation program

Abstract

A demonstration simulation program was developed on an IBM AT personal com puter to aid students in understanding the effects of altering rate constants on simple one and two compartment pharmacokinetic models. This menu driven system graphi cally presents specific sets of simulated curves illustrating how all components of a model interact. The student selects one of the five models and also determines which portion of the model is to be altered. The aim of the program is to teach the user to anticipate the outcome of the model alteration and interactions. The program was developed with the use of PC Storyboard, a demonstration software package, which provided the tools necessary for an elegant program presentation. This interactive presentation graphic program illustrates a viable means of conveying simulation models to a novice audience.

Keywords

demonstration simulation pharmacokinetic model PC storyboard personal computer hybrid computer

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References

Pearce, B.A. and J.F. Young. 1981. "A hybrid computer system for pharmacokinetic modeling. I. Software considerations." Proc. Summer Computer Simulation Conf, pp. 117-121.

StruBAS, Version 2.0, Structured BASIC Development System, 1983, User's Guide, Laney Systems, Inc., Little Rock, AR.

Young, J.F. , C.G. White and B.A. Pearce. 1981. "A hybrid computer system for pharmacokinetic modeling. II. Applications." Proc. Summer Computer Simulation Conf, pp. 122-129.