Several of the important fluid dynamics problems en countered in the design, analysis, and control of cardio- circulatory assist devices are well suited to examination (and solution) by hybrid computer simulation.
The simulation approach to the analysis and control synthesis for a particular left ventricular assist blood pump, pneumatic drive system, and experimental animal is presented. This includes a hybrid computer simulation of this system, sensitivity analysis, solution for control parameters, and description of a computer monitoring and control system to regulate the assist device.
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References
1.
Cooley D.A.Liotta D. et al Discussion: first human implantation of cardiac prosthesis for staged total replacement of the heartTransactions American Society Artificial Internal Organs vol 91969 p 252
2.
Doorman F.Bernstein E.F. et alProgress in the design of a centrifugal cardiac assist pump with trans-cutaneous energy transmission by magnetic couplingTransactions American Society Artificial Internal Organs vol 91969 p 441
3.
Tomecek J.Jaron D. et alPhase shift cardiac assistance with a valve balloon: experimental resultsTransactions American Society Artificial Internal Organs vol 91969 p 406
4.
5.
Rideout V.C.Dick D.E.Difference-differential equations for fluid flow in distensible tubesIEEE Transactions on Biomedical Engineering vol 141967 p 171
6.
Rideout V.C.Dick D.E.Letter to the EditorSIMULATION April 1968 p 169
7.
8.
9.
10.
11.
12.
Sarnoff S.J. et alHemodynamic determinants of oxygen consumption of the heart with special reference to the tension-time indexAmerican Journal Physiology vol 1921958 p 148
13.
Liotta D.C. et alIn vitro and in vivo flow studies in blood pumps TransactionsAmerican Society Artificial Internal Organs vol 131967 p 280
14.
Hiller K.W.Seidel W.Kolff W.A servo-mechanism to drive an artificial heart inside the chest TransactionsAmerican Society Artificial Internal Organs vol 81962 p 125
15.
Kirsch V.E. et alLeft ventrical bypass in experimental left heart failure Transactions American Society Artificial Internal Organs vol 121966 p 53
16.
17.
18.
Robins H.Monro S.A stochastic approximation methodAnnals of Mathematical Statistics vol 221951 p 400
