In this paper we discuss the main elements of an approach to teach simulation discipline in a small university with an interdisciplinary specialization in pharmaceutics, biology, health sciences, and computer science which are combined into a health sciences curriculum. We analyze existing ways to teach simulation courses and identify the specificity and goals within our approach. We propose the content of a simulation course sequence for the mentioned type of university. It includes three units: general simulation methodology, case studies, and building of real simulation models. The proposed new approach reinforces the problem-solving skills of students and their opportunities to conduct applied research. We implemented the proposed approach in a simulation course sequence and we successfully conducted student research projects.
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