Meningococcal Disease: Hope on the Horizon

Anon. Meningococcal outbreak in Wales. SCIEH Weekly Report; 33 (99/07): 61

Ala'Aldeen DAA , Neal K , Nguyen-Van-Tam J , Ait-Tahar K , Slack RC . Dynamics of meningococcal carriage among first year university students in United Kingdom. In: Programme and Abstracts of the 2nd Annual Meeting, British Infection Society 1999.

Greenwood BM . Meningococcal infection. In: Oxford Textbook of Medicine, third edition (Eds. Weatherall DJ , Ledingham JGG , Warrell DA ). Chapter 7.11.5: 533–44

Harrison LH , Armstrong CW , Jenkins SR , Harman MW , Ajello GW , Miller JB jr A cluster of meningococcal disease on a school bus following epidemic influenza. Arch Int Med 1991; 151: 1005–1009

Fischer M , Hedberg K , Cardosi P , Plikaytis BD , Hoesly FC , Steingart KR Tobacco smoke as a risk factor for meningococcal disease. Pediatr Infect Dis J 1997; 16 (10): 979–83

MacKinnon FG , Borrow R , Garringe AR , Fox AJ , Jones DM , Robinson A. Demonstration of lipopolysacharide immunotype and capsular virulence factors for Neisseria meningitidis. Microbial Pathogenesis 1993; 15: 359–66

Nadel S , Newport MJ , Booy R , Levin M. Variation in the tumour necrosis factor alpha gene promotor region may be associated with death from meningococcal disease. J Infect Dis 1996; 174 (4): 878–80

Riordan FA , Marzouk O , Thomson AP , Sills JA , Hart CA . Proinflammatory and anti-inflammatory cytokines in meningococcal disease. Arch Dis Child 1996; 75 (5): 453–54

Kornelisse RF , Hazeizet JA , Savelkoul HF , Hop WC , Suur MH , Borsboom AN The relationship between plasminogen activator inhibitor-1 and proinflammatory and counterinflammatory mediators in children with meningococcal septic shock. J Infect Dis 1996; 173 (5): 1148–56

Riordan FA , Thomson AP , Sills JA , Hart CA . Prospective study of ‘door to needle time’ in meningococcal disease. J Accid Emerg Med 1998 Jul; 15 (4) 249–51

Granier S , Owen P , Stott NCH . Recognising meningococcal disease: the case for further research in primary care. Br J Gen Pract 1998; 48: 1167–1171

Cartright K , Reilly S , White D , Stuart J. Early treatment with parental penicillin in meningococcal disease. Br Med J 1992; 305: 143–47

Begg N , Cartwright KAV , Cohen J , Kaczmarski EB , Innes JA , Leen CLS , Nathwani D and the British Infection Society Working Party. Consensus statement on diagnosis, investigation, treatment and prevention of acute bacterial meningitis in immunocompetent adults. J Infect 1999; 39: 1–15.

Newcombe J , Cartwright K , Palmer WH , McFadden J. PCR of peripheral blood for diagnosis of meningococcal disease. J Clin Microbiol 1996 Jul; 34 (7): 1637–40

Perriapparum M , Taylor MR , Keane CT . Rapid detection of meningococci from petechiae in acute meningococcal infection. J Infect 1995 Nov;31 (3) 201–325.

Galimand M , Gerbaud G , Guibourdenche M , Riou J , Courvalin P. High level chloramphenicol resistance in Neisseria meningitidis . N Eng J Med 1998; 339: 868–74

Giroir BP , Quint PA , Barton P , Kirsch EA , Kitchen L , Goldstein B Preliminary evaluation of recombinant amino-terminal fragment of human bactericidal permeability protein in children with meningococcal sepsis. Lancet 1997; 350: 1439–43

Department of Health. Meningococcal. In: Immunisation against Infectious Diseases, 1996: 150

Smith OP , White B , Vaughan D , Rafferty M , Lyons B , Casey W. Use of protein-C concentrate, heparin fulminans, and haemodiafiltration in meningococcus induced purpura fulminans. Lancet 1997; 350: 1590–93

Slack MP , Azzopardi HJ , Hargreaves RM , Ramsay ME . Enhanced surveillance of invasive Haemophilus influenzae disease in England, 1990 to 1996: impact of conjugate vaccines. Paediatr Infect Dis J 1998; 17 (suppl 9): S204–207

Lieberman JM , Chiu SS , Wong VK , Partidge S , Chang SJ , Chiu CY Safety and immunogenecity of a serogroups A/C Neisseria meningitidis oligosaccharide protein conjugate vaccine in young children. A randomised control trial. JAMA 1996; 275 (19): 1499–1503

Fairley CK , Begg N , Fox AJ , Jones DM , Cartwright K. Conjugate meningococcal serogroup A and C vaccine: reactogenicity and immunogenicity in United Kingdom infants. J Infect Dis 1996; 174 (6); 1360–63

MacDonald NE , Halperin SA , Law BJ , Forrest B , Danzig LE , Granoff DM . Induction of immunological memory by conjugated vs plain meningococcal Cholysaccharide vaccine in toddlers: a randomized controlled trial. JAMA 1998; 280 (19): 1685–89

Harrison LH , Dwyer DM , Maples CT , Billman L. Risk of meningococcal infection in college students. JAMA 1999; 281 (20) 1906–1910

Department of Health. Meningococcal. In: Immunisation against Infectious Diseases, 1996: 152

Goldblatt D. Recent developments in bacterial conjugate vaccines. J Med Microbiol. 1998; 47: 563–67

Wenger JD . Serogroup B meningococcal disease. New outbreaks, new strategies. JAMA 1999; 281 (16).1541–43

Tappero JW , Lagos R , Ballesteros AM Immunogenecity of 2 serogroup b outer-membrane protein meningococcal vaccines; a randomised controlled trial in Chile. JAMA 1999; 281: 1520–27

Sheldon T. Meningitis B vaccine looks promising. Br Med J 1998; 317: 770

Smart LE , Christie P , Clarke SC , Reid JA , Thom L , Denham BC , Edwards GFS . Meningococcal disease in Scotland 1997. SCIEH Weekly Report; 33 (99/01): 2–6