Asplenic individuals are known to be at a higher risk of developing serious and occasionally fatal sepsis. Prophylactic measures are generally recommended for the first few years post-splenectomy. We report two cases of severe Pneumococcal Sepsis occuring more than 10 years post-splenectomy leading to prolonged hospitalisation and long term morbidity and suggest that Prophylactic Penicillin should be taken life-long.
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