Non-Hodgkin's lymphoma (NHL) commonly presents with extensive disease involving extranodal tissues. Involvement of the mediastinal and hilar lymph nodes, pleura and lung parenchyma are recognised complications although their incidence is uncertain. However pulmonary involvement is undoubtedly much less common than involvement at other extra nodal sites. Histologically proven NHL limited to the lung parenchyma, after full staging including computerised tomography and marrow trephines, is extremely rare. We report on two such cases and review the literature.
FillyRBlankNCastellinoRA. Radiographic distribution of intrathoracic disease in previously untreated patients with Hodgkin's disease and non-Hodgkin's lymphoma. Diagnos Radiol1976; 120: 277–281.
3.
RosenbergSADiamondHDJaslowitzBCraverLF. Lymphosarcoma: A review of 1269 cases. Medicine1961; 40: 31–84.
4.
ManoharanAPitneyWRSchonellMEBaderLV. Intrathoracic manifestations in non-Hodgkin's lymphoma. Thorax1979; 34: 29–32.
5.
JonesSEFuksZBullM, el al. Non-Hodgkin's lymphomas: Clinicopathologic correlation in 405 cases. Cancer1973; 31: 806–823.
6.
KossMNHochholzerLNicholsPWWehuntWDLazarusAA. Primary non-Hodgkin's lymphoma and pseudolymphoma of lung. Hum Pathol1983; 14: 1024–1038.
7.
TurnerRRColbyTVDoggettRS. Well differentiated lymphocytic lymphoma: A study of 47 patients with primary manifestation in the lung. Cancer1984; 54: 2088–2096.
8.
JenkinsPFWardMJDaviesPFletcherJ.Non-Hodgkin's lymphoma, chronic lymphatic leukaemia and the lung. Br J Dis Chest1981; 75: 22–30.
9.
AndersonKCLeonardRCFCanellosGPSkarinATKaplanWD. High dose gallium scanning in lymphoma. Ann Intern Med1983; 75: 327–331.
10.
BestJJKBlackledgeGForbesWStC,. Computed tomography of abdomen in staging and clinical management of lymphoma. Br Med J1978; 2: 1675–1677.
11.
MacdonaldJB. Lung involvement in Hodgkin's disease. Thorax1977; 32: 664–667.
12.
WhitcolmMESchwarzMIKellerARFlanneryEPBlomJ.Hodgkin's disease of the lung. Am Rev Respir Dis1972; 106: 79–84.
