The prevalence of anti-HAV in blood donors in West Scotland and in children admitted to a Glasgow hospital was determined. By the age of five years, 16% of the children had antibody and at 15 years, 30%. In adults, prevalence continued to rise with age, with 78% of those over 40 years showing evidence of past infection. Cases of acute hepatitis A in West Scotland have declined since 1983. At present the peak age group for infection is 25–34 years whereas in the early 80s the peak group was five to 14 years.
MathiesonLRSkinhojPBalstrupF.Antibody to hepatitis A virus in plasma of Danish blood donors and in immune serum globulin produced in Denmark. Scand J Infec Dis1980; 12: 81–83.
2.
FollettEACMcMichaelSStewartJCromackS.Acute hepatitis A in 1981. A change in pattern. Scot Med J1983; 28: 30–33.
3.
FollettEACBarrACrawfordRJMitchellR.Viral hepatitis A markers in blood donors and patients with a history of jaundice. Lancet1980; 1: 246–249.
4.
MortimerPPParryJV. Anti-Hepatitis-A-Virus potency of immunoglobulin. Lancet1981; I: 1364–1365.
5.
IwarsonSFrösnerGLindholmANorkransG.The changed epidemiology of hepatitis A infection in Scandinavia. Scand J Infect Dis1978; 10: 155–156.
6.
CreweMDEmbilJAGarnerJB. Prevalence of antibodies to hepatitis A virus in Nova Scotia children. Can Med Assoc J1983; 128: 1195–1197.
7.
ElkanaYBarkayA.Antibodies to hepatitis A in young Israeli children. J Infect1982; 4: 57–62.
8.
TandonBNGandhiBMJoshiYKGuptaHIrshadN.Subclinical hepatitis A in North Indian children. Lancet1984; I: 335–336.
