Nomifensine is a widely used antidepressant agent with few side-effects but haemolytic anaemia with acute renal failure has been reported with both intermittent therapeutic dosage and self-inflicted overdose. We report here a case of acquired immune haemolytic anaemia with acute renal failure induced by second exposure to a single capsule of nomifensine.
PrescottLFIllingworthRNCritchleyJAJHFrazerIStirlingML. Acute haemolysis and renal failure after nomifensine overdose. Br Med J1980; 281: 1392–1393
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SalamaASantosoSMueller-EckhardtC.The heterogeneity of nomifensine-induced red blood cell antibodies: The use of ex vivo antigens for their detection. (Abstract) Blood1984; 64Suppl 1: 90A
