Twenty-one patients with recurrent deep venous thrombosis were treated with an anabolic steroid (Δ4-ethyloestrenol) for up to 56 months. All had been shown to have a deficient fibrinolytic response to vascular occlusion and/or low vessel wall plasminogen activator content.
Therapy resulted in improvement in clinical and fibrinolytic parameters and no significant side effects were seen.
