The effects of bromocriptine were studied in 29 patients with acromegaly. The majority showed significant suppression of growth hormone secretion, often with symptomatic benefit.
The drug is a useful adjunct to primary methods of treatment, especially pituitary irradiation, but regular assessment of whether it is continuing to have a suppressive effect should be undertaken.
EastmanRCGordenPRothJ. Conventional supervoltage irradiation is an effective treatment for acromegaly. Journal of Clinical Endocrinology and Metabolism1979; 48: 931–940.
HunterWM. Methods of Hormone Analysis Eds. BreuerHHamelDKrüskemperHL. 1976; Wiley (New York).
4.
BrooksAPStephenPJNairnIMStrongJA. Bromocriptine and acromegaly: therapeutic implications. Journal of Royal Society of Medicine.1979; 72: 562–564.
5.
McGregorAMScanlonMFHallRHallK. Effect of bromocriptine on pituitary tumour size. British Medical Journal, 1979; 2: 700–703.
6.
BesserGMThornerMOWassJAH. Bromocriptine treatment of acromegaly. Pharmacological and Clinical Aspects of Bromocriptine (Parlodel). Proceedings of Symposium 1976 Sandoz.
7.
BesserGMWassJAHThornerMO. Acromegaly: Results of long term treatment with bromocriptine. Acta Endocrinologica, 1978; 88: Suppl. 216: 187–198.
8.
LundinLLjunghallSWidtLBoströmH. Bromocriptine therapy in eleven patients with acromegaly. Acta Endocrinologica1978; 88: Suppl. 216: 207–216.