A young woman who developed a cerebral venous thrombosis shortly after commencement of an oral contraceptive preparation was subsequently found to have paroxysmal nocturnal haemoglobinuria. The aetiology of thrombotic complications in this condition is discussed, with particular reference to the additional risk factor of the contraceptive pill in this case.
Get full access to this article
View all access options for this article.
References
1.
DacieJVLewisSM. Paroxysmal nocturnal haemoglobinuria, clinical manifestations, haematology and nature of the disease. Ser Haematol1972; 5: 3–23
2.
PeytremannRRhodesRSHartmanRC. Thrombosis in PNH with particular reference to progressive diffuse hepatic thrombosis. Ser Haematol1972; 5: 115–136
3.
DacieJVLewisSM. Practical haematology, 5th Edition. Edinburgh, London and New York: Churchill Livingstone, 1975; 305–307