Screening by Culture for the Detection of Gonorrhoea in Women

Abstract

The number of gonoccal infections detected by each of three sets of diagnostic cultures from the urethra, cervix, rectum and occasionally the throat, were Calculated for 1976 when Thayer Martin (TM) medium was used and for 1977 when Modified New York City (MNYC) medium was used.

In [1977, 98.7 per cent (451/457) of the total infections diagnosed were confirmed by culture compared with 88.3 per cent (324/367) of infections diagnosed in 1976 (P<0.001). The first set of diagnostic tests detected 97.6 per cent (440/451) of culture-positive infections in 1977 compared with only 88.9 per cent (228/324) in 1976 (P<0.001). The efficiency of screening with a single endocervical culture was also calculated. This procedure would have detected 90.2 per cent (407/451) of culture-positive infections in 1977 when MNYC medium was used compared with only 78.1 per cent (253/324) in 1976 when TM medium was used (P<0.001). It is suggested that the statistically significant improvement in the culture results for 1977 resulted from the introduction of MNYC medium since all other diagnostic procedures were identical to those in 1976. Other advantages associated with the use of MNYC medium are discussed.

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References

Adler

M. W.

(1978). Diagnostic treatment and reporting criteria for gonorrhoea in sexually transmitted disease clinics in England and Wales: I. Diagnosis. British Journal of Venereal Diseases, 54, 10.

Barlow

Nayyar

Phillips

Barrow

(1976). Diagnosis of gonorrhoea in women. British Journal of Venereal Diseases, 52, 326.

Bhattacharyya

M. N.

Jephcott

A. E.

Morton

R. S.

(1973). Diagnosis of gonorrhoea in women: Comparison of sampling sites. British Medical Journal, 2, 748.

Brorson

J. E.

Holmberg

Nygren

Seeberg

(1973). Vancomycin-sensitive strains of Neisseria gonorrhoea. A problem for the diagnostic laboratory. British Journal of Venereal Diseases, 49, 452.

Chipperfield

E. J.

Catteral

R. D.

(1976). Reappraisal of Gram-staining and cultural techniques for the diagnosis of gonorrhoea in women. British Journal of Venereal Diseases, 52, 36.

Evans

B. A.

(1976). Detection of gonorrhoea in women. British Journal of Venereal Diseases, 52, 40.

Faur

Y. C.

Weisburd

M. H.

Wilson

M. E.

May

P. S.

(1973). A new medium for the isolation of pathogenic Neisseria (NYC medium). I. Formulation and comparisons with standard media. Health Laboratory Science, 10, 44.

Nicol

C. S.

, (1976). World Trends in Sexually Transmitted Diseases: The situation in the United Kingdom. In Sexually Transmitted Diseases, pp 13–25. Edited by Catteral

R. D.

Nicol

C. S.

London, New York and San Francisco: Academic Press.

Norins

L. C.

(1974). The case for gonococcal serology (Editorial). The Journal of Infectious Diseases, 130, 677.

10.

Schmale

J. D.

Martin

J. E.

Domescik

(1969). Observations on the culture diagnosis of gonorrhoea in women. Journal of the American Medical Association, 210, 312.

11.

Wiesner

P. J.

Jones

O. G.

Blount

J. M.

(1976). World Trends in Sexually Transmitted Diseases: The situation in the United States. In Sexually Transmitted Diseases, pp 5–13. Edited by Catteral

R. D.

Nicol

C. S.

London, New York and San Francisco: Academic Press.

12.

Young

(1978a). Cultural diagnosis of gonorrhoea with modified New York City (MNYC) medium. British Journal of Venereal Diseases, 54, 36.

13.

Young

(1978b). Identification and Penicillinase Testing of Neisseria gonorrhoeae from Primary Isolation Cultures on Modified New York City Medium. Journal of Clinical Microbiology, 7, 247.