Abstract
Of 50 strains of Haemophilus influenzae isolated from purulent sputum specimens, 100 per cent were fully sensitive to chloramphenicol, all of them being more sensitive than the Staphylococcus aureus (Oxford strain) control.
Only 36 per cent were fully sensitive to ampicillin, but the other 64 per cent were moderately sensitive; none were resistant.
Eighty four per cent were fully sensitive to tetracycline, 38 per cent to sulpha-methoxazole and 74 per cent to trimethoprim.
None of the strains were fully sensitive to penicillin or clindamycin. Only 32 per cent of strains were moderately sensitive to clindamycin and the rest were completely resistant. Reports that Haemophilus influenzae is sensitive to clindamycin are thought to be in error.
Conclusions are drawn from these results which might influence antibiotic treatment of exacerbations of chronic bronchitis.
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