Urinary radioactivity following the simultaneous oral administration of Vitamin B12, labelled with 2 isotopes of cobalt (‘Dicopac’ test), was measured in 20 control subjects and in 20 patients suffering from pernicious anaemia: one isotope was bound to normal human gastric juice, while the other was free. The test was simple to perform and while the majority of results were of diagnostic value, some equivocal results were also obtained.
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