A double-blind trial was undertaken to assess the effect of bendro-fluazide in lowering the blood pressure in patients with essential hypertension controlled on propranolol. An increased hypotensive effect was found and the greatest fall occurred in the supine systolic blood pressure. Side-effects were mild and transient and did not interfere with treatment.
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References
1.
AndersonJ.GodfreyB. E.HillD. M.Munro-FaureA. D.SheldonJ. (1971). A comparison of the effect of hydrochlorothiazide and frusemide in the treatment of hypertensive patients. Quarterly Journal of Medicine, 40, 541.
2.
PrichardB. N. C.GillamP. M. S. (1964). Use of propranolol (Inderal) in the treatment of hypertension. British Medical Journal, 2, 725.
3.
PrichardB. N. C.GillamP. M. S. (1969). Treatment of hypertension with propranolol. British Medical Journal, 1, 7.
4.
Veterans Administrative Co-operative Study Group on Antihypertensive Agents. (1967). Journal of the American Medical Association, 202, 1028.
5.
Veterans Administrative Co-operative Study Group on Antihypertensive Agents. (1970). Journal of the American Medical Association, 213, 1143.
6.
ZachariasF. J.CowenK. J. (1970). Controlled trial of propranolol in hypertension. British Medical Journal, 1, 471.
7.
ZachariasF. J.CowenK. J. (1971). Propranolol in hypertension: a 5 year study. Postgraduate Medical Journal (January supplement), 47, 75.
