Drug Metabolism

Beckett A. H. , Triggs E. J. (1967). Enzyme induction in man caused by smoking. Nature, 216, 5115

Becking G. C. , Morrison A. B. (1970). Hepatic drug metabolism in zinc-deficient rats. Biochemical Pharmacology, 19, 895

Brodie B. B. , Axelrod J. (1950). The fate of antipyrine in man. Journal of Experimental Pharmacology and Therapeutics, 98, 97

Brodie B. B. (1964). Distribution and fate of drugs. In Absorption and Distribution of Drugs, p. 199 Edited by T. B. Binns, Edinburgh: Livingstone

Brook R. , Schrogie J. J. , Solomon H. M. (1968). Failure of probenecid to inhibit the rate of metabolism of tolbutamide in man. Clinical Pharmacology and Therapeutics, 9, 314

Burns J. J. , Conney A. H. (1965). Enzyme stimulation and inhibition in the metabolism of drugs. Proceedings of the Royal Society of Medicine, 58, 955

Catz C. S. , Juchau M. R. , Yaffe S. J. (1970). Effects of iron, riboflavin and iodide deficiencies on hepatic drug-metabolising enzyme systems. Journal of Pharmacology and Experimental Therapeutics, 174, 197

Christensen L. K. , Skovsted L. (1969). Inhibition of drug metabolism by chloramphenicol. Lancet, 2, 1397

Conney A. H. (1967). Pharmacological implications of microsomal enzyme induction. Pharmacological Reviews, 19, 317

Conney A. H. , Welch R. M. , Kuntzman R. , Burns J. J. (1967). Effects of pesticides on drug and steroid metabolism. Clinical Pharmacology and Therapeutics, 8, 2

Crawford J. S. , Rudofsky S. (1966). Some alterations in the pattern of drug metabolism associated with pregnancy, oral contraceptives and the newly-born. British Journal of Anaesthesia, 38, 446

Cucinell S. A. , Conney A. H. , Burns J. J. (1965). Drug Interactions in Man. Clinical Pharmacology and Therapeutics, 6, 420

Davies D. , Gigon P. , Gillette J. R. (1967). Species differences in ethylmorphine demethylation, the amount of P-450 and ethylmorphine-induced spectral changes in liver microsomes. Pharmacologist, 9, 203

Dent C. E. , Richens A. , Rowe D. J. F. , Stamp T. C. B. (1970). Osteomalacia with long-term anticonvulsant therapy in epilepsy. British Medical Journal, 4, 69

Edwards J. A. , Evans D. A. Price (1967). Ethanol metabolism in subjects possessing typical and atypical liver alcohol dehydrogenase. Clinical Pharmacology and Therapeutics, 8, 824

Gillette J. R. (1967). Individually different responses to drugs according to age, sex and function or pathological state. In Drug Responses in Man, p. 24. Edited by Wolstenholme G. and Porter R . London: Churchill

Hart L. G. , Shultice R. W. , Fouts J. R. (1963). Stimulating effects of chlordane on hepatic microsomal drug metabolism. Toxicology and Applied Pharmacology, 5, 371

Kato R. , Takanaka A. (1968). Metabolism of drugs in old rats. Japanese Journal of Pharmacology, 18, 4

Kolmodin B. , Azarnoff D. L. , Sjoqvist F. (1969). Effect of environmental factors on drug metabolism: Decreased plasma half-life of antipyrine in workers exposed to chlorinated hydrocarbon insecticides. Clinical Pharmacology and Therapeutics, 10, 638

Kreek M. J. , Sleisinger M. J. (1968). Reduction of serum unconjugated bilirubin with phenobarbitone in adult congenital, non-haemolytic unconjugated hyperbilirubinaemia. Lancet, 2, 73

Kuntzman R. , Mark L. C. , Brand L. , Jacobson M. , Levin W. , Conney A. H. (1966). Metabolism of drugs and carcinogens by human liver enzymes. Journal of Pharmacology and Experimental Therapeutics, 152, 151

Kutt H. , Wolk M. , Scherman R. , McDowell F. (1964). Insufficient parahydroxylation as a cause of diphenylhydantoin toxicity. Neurology, 14, 542

Levi A. J. (1968). Poisoning, In Recent Advances in Medicine, 15th edition, p. 95.

Levi A. J. , Sherlock S. , Walker D. (1968). Phenylbutazone and isoniazid metabolism in patients with liver disease in relation to previous drug therapy. Lancet, 1, 1275

Lombrozo L. , Mitoma C. , Neubauer S. E. (1968). Stimulation of drug metabolism by caffeine. Federation Proceedings, 27, 301

MacDonald M. G. , Robinson D. S. , Sylwester D. , Jaffe J. J. (1969). The effects of phenobarbital, chloral betaine, and glutethimide administration on warfarin plasma levels and hypoprothrombinemic responses in man. Clinical Pharmacology and Therapeutics, 10, 80

O'Malley K. , Stevenson I. H. , Alexander W. (1970). Increased antipyrine half-life in women taking oral contraceptives. Scottish Medical Journal, 15, 454

O'Malley K. , Crooks J. , Duke E. , Stevenson I. H. (1971). The effects of age and sex on human drug metabolism. British Medical Journal, 3, 607

Parke D. V. (1968). The Biochemistry of Foreign Compounds. Oxford: Pergamon Press

Evans D. A. Price (1968). Pharmacological genetics. In Fourth Symposium on Advanced Medicine, p. 226. Edited by Wrong O . London: Pitman

Radzialowski F. M. , Bousquet W. F. (1968). Daily rhythmic variation in hepatic drug metabolism in the rat and mouse. Journal of Pharmacology and Experimental Therapeutics, 163, 229

Renwick A. G. , Williams R. T. (1970). The metabolism of cyclamate. Proceedings of the First International Sugar Research Conference, p. 3.

Rubin E. , Lieber C. S. (1968). Hepatic microsomal enzymes in man and rat: Induction and inhibition by ethanol. Science, 162, 690

Shahidi N. T. (1968). Acetophenetidin-induced methemoglobinemia. Annals of the New York Academy of Sciences, 151, 822

Sjoqvist F. (1965). Interaction between monoamine oxidase inhibitors and other substances. Proceedings of the Royal Society of Medicine, 58, 967

Solomon H. M. (1968). Variations in metabolism of coumarin anticoagulant drugs. Annals of the New York Academy of Sciences, 151, 932

Stevenson I. H. , Turnbull M. J. (1968). Hepatic drug-metabolising enzyme activity and duration of hexobarbitone anaesthesia in barbitone-dependent and withdrawn rats. Biochemical Pharmacology, 17, 2297

Stevenson I. H. , O'Malley K. , Ballinger B. B. (1970). Drug-metabolising capacity and drug-dependence. Clinical Science, 39, 11p

Tschudy D. P. (1968). Clinical aspects of drug reactions in hereditary hepatic porphyria. Annals of the New York Academy of Sciences, 151, 850

Vesell E. S. (1969). Recent Progress in Pharmacogenetics, Advances in Pharmacology and Chemotherapy, 7, 1

Von Wartburg J. P. , Schurch P.M. (1968). Atypical human liver alcohol dehydrogenase. Annals of the New York Academy of Sciences, 151, 936

Welch R. M. , Harrison Y. E. , Gommi B. W. , Poppers P. J. , Funster M. , Conney A. H. (1969). Stimulatory effect of cigarette smoking on the hydroxylation of 3, 4-benzpyrene and the N-demethylation of 3-methyl-4-monomethylamino-azobenzene by enzymes in human placenta. Clinical Pharmacology and Therapeutics, 10, 100