The results of treatment of 45 patients with nephroblastoma in the period 1953–1968 are presented. The overall three year survival rate is 27% while for those given radiotherapy and repeated courses of Actinomycin D following operation the three year survival rate is 40%. The results reported from other centres are discussed.
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References
1.
BaertL., VerduynH., VereeckenR. (1866). Wilms Tumour (nephroblastoma) : Report of 57 histologically proved cases. Journal of Urology, 96, 871
2.
CochranW., FroggattP. (1967). Bilateral nephroblastoma in two sisters. Journal of Neurology, 97, 216
3.
FarberS. (1966). Chemotherapy in the treatment of leukaemia and Wilms' tumour. Journal of the American Medical Association, 198, 826
4.
FarberS., D'AngioG., EvansA., MinisA. (1960). Clinical studies of Actinomycin D with special reference to Wilm's tumour in children. Annals of the New York Academy of Science, 89, 421
5.
HastingsN., GwinnJ. L. (1965). Retroperitoneal tumours in infants and children. American Journal of Surgery, 110, 203
6.
HigginsT. T. (1955). Malignant disease in childhood with special reference to neoplasm of the urogenital tract and sympathetic chain. Glasgow Medical Journal, 36, 428
7.
JohnstonJ. H., MainwaringD., RickhamP. P. (1969). Ten years experience with Actinomycin D in the treatment of nephroblastoma. Kinderchirurgie, Supplement zu band, 6, 171
8.
JohanssonJ., RosengrenB. (1967). Wilms tumour: Results of treatment by early post-operative radiotherapy. British Journal of Radiology, 40, 516
9.
KlapporthH. J. (1959). Wilms' tumour: A report of 45 cases and an analysis of 1351 cases reported in the world literature from 1940–1958. Journal of Urology, 81, 633
10.
MaierJ. G., HarshawW. G. (1967). Treatment and prognosis in Wilms turnout. A study of 51 cases with special reference to the role of Actinomycin D. Cancer, 20, 96
11.
MartinL. W., ReyesP. M. (1969). An evaluation of 10 year's experience with retroperitoneal lymph node dissection for Wilms' tumour. Journal of Paediatric Surgery, 6, 683
12.
ParkkulainenK. V., SirolaK., SulamaaM. (1965). Results in the treatment of Wilms tumour. Annales Paediatriae Fenniae, 11, 134
13.
ScottL. S. (1954). Renal tumours in childhood. Glasgow Medical Journal, 35, 33
14.
VaethJ. M., LevittS. H. (1963). Five years results in the treatment of Wilms tumour of children. Journal of Urology, 90, 247
15.
WilliamsD. I., YoungD. G. (1968). Malignant tumours of the genito-urinary tract in childhood.
16.
WolffJ. R., LebhezT. B. (1968). Single versus multiple dose Dactinomycin therapy of Wilms' tumour. American Journal of Obstetrics and Gynecology, 100, 1151
17.
YoungD. G., WilliamsD. I. (1969). Malignant renal tumours in infancy and childhood. British Journal of Hospital Medicine, 2, 741
