An unusually severe and prolonged salmonella enteritis is described in 6 adults; 5 had previously undergone gastric surgery and one had pernicious anaemia. Possible causes are discussed but the probable common aetiological factor was deficient gastric juice. Hypo- or achlorhydric subjects appear more prone to salmonellosis and may become seriously ill as a result. Any diarrheal illness in them should be investigated by the bacteriologist before being attributed to altered physiology alone.
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References
1.
BlackP. H.KunzL. J.SwartzM. N. (1960). Salmonellosis—a review of some unusual aspects (continued). New England Journal of Medicine, 262, 864.
2.
BoothC. C.TabaqchaliS. (1968). In Fourth Symposium on Advanced Medicine, p. 248. Edited by Wrong. London: Pitman Medical
3.
ChristieA. B. (1969a). In Infectious Diseases: Epidemiology and Clinical Practice, p. 22–29. Edinburgh: E. & S. Livingstone
4.
ChristieA. B. (1969b). In Infectious Diseases: Epidemiology and Clinical Practice, p. 39–40. Edinburgh: E. & S. Livingstone.
5.
CreganJ.DunlopE. E.HaywardN. J. (1953). The bacterial content of human small intestine in disease of the stomach. British Medical Journal, 2, 1248
6.
CreganJ.HaywardN. J. (1953). The bacterial content of the healthy human small intestine. British Medical Journal, 1, 1356
7.
DellipianiA. W.GirdwoodR. H. (1964). Bacterial changes in the small intestine in malabsorptive states and in pernicious anaemia. Clinical Science, 26, 359.
8.
DixonJ. M. S. (1960). The fate of bacteria in the small intestine. Journal of Pathology and Bacteriology, 70, 131
9.
DrasarB. S.ShinerM.McLeodG. M. (1969). Studies on the Intestinal Flora I. The bacterial flora of the gastro-intestinal tract in healthy and achlorhydric persons. Gastroenterology, 56, 71
10.
GorbachS. L.PlautA. G.NahasL.WeinsteinL.SplanknebelG.LevitanR. (1967). Studies of Intestinal Microflora, II. Microorganisms of the small intestine and their relations to oral and faecal flora. Gastroenterology, 53, 856
11.
HarrisonG. A. (1957). In Chemical Methods in Clinical Medicine, 4th Edition, p. 79–80. London: J. & A. Churchill
12.
KnottF. A. (1927). Addison's (Pernicious) anaemia and subacute combined degeneration of the cord: The role of achlorhydria and intestinal infection. Guy's Hospital Report, 77, 1
13.
MeynellG. G. (1955). Some factors affecting the resistance of mice to oral infections by Salm. typhimurium. Proceedings of the Royal Society of Medicine, 48, 916
14.
ShinerM.WatersT. E.GrayJ. D. A. (1963). Culture studies of the gastrointestinal tract with a newly devised capsule. Gastroenterology, 45, 625
15.
WaddellW. R.KunzL. J. (1956). Association of Salmonella enteritis with operations in the stomach. New England Journal of Medicine, 255, 555
16.
WaddellW. R.WangC. C. (1952). Experimental studies in human gastric physiology, I. The effect of fat upon gastric evacuation after partial gastrectomy. Annals of the New York Academy of Sciences, 56, 83
