Pulmonary granular cell tumours: case presentations and literature review

Abstract

Pulmonary granular cells tumours are very rare tumours, most probably originating from Schwann cells. Although rare, clinical and biological presentation is diverse. They are most commonly endobronchial masses, usually a solitary pulmonary lesion, although in up to 20% they can occur as multiple lesions and can be mistaken for malignant process. In spite of infiltrative growth, and rare direct lymph node invasion, they have a very good prognosis if completely removed. Here we present two cases from the archives of the Institute of Pathology, University of Zagreb School of Medicine, with literature review.