A five year old girl with Neimann-Pick disease type C subsequently developed Crohn's Disease. This association has only been presented once previously in the literature. This report discusses the options for managing one chronic disease in the presence of another life limiting condition.
ImrieJ, WraithJE. Isolated splenomegaly as the presenting feature of Neimann- Pick disease type C. Arch Dis Child2001; 84 (5): 427–429
2.
KellyDA, PortmannB, MowatAP, SherlockS, LakeBD. Neimann-Pick disease type C: diagnosis and outcome in children, with particular reference to liver disease. J Pediatr1993; 123 (2): 242–247
3.
JolliffeDS, SarkanyI. Neimann-Pick type III and Crohn's disease. J R Soc Medi1983; 76: 307–308
4.
StephensMC, ShepanskiMA, MamulaP, MarkowitzJE, BrownKA, BaldassanoRN. Safety and steroid- sparing experience using infliximab for Crohn's disease at a pediatric inflammatory bowel disease center. Am J Gastroenterol2003; 98 (1): 104–111
5.
HyamsJS, MarkowitzJ, WyllieR. Use of infliximab in the treatment of Crohn's disease in children and adolescents. J Pediatr2000; 137 (2): 192–196
