We report the case of identical twin sisters, both with hypertrophic cardiomyopathy, and both found to have similar echocardiographic appearances in the form of asymmetric septal hypertrophy. This is unusual, in that published reports commonly describe the heterogeneous expression of this condition in twins.
ClarkCE, HenryWL, EpsteinSE. Familial prevalence and genetic-transmission of idiopathic hypertrophic cardiomyopathy. N Engl J Med1973; 289: 709–714
2.
van DorpWG, ten CateFJ, VletterWB, DohmanH.RoelandtJ. Familial prevalence of asymmetric septal hypertrophy. Eur J Cardiol1976; 4: 349–351
3.
MaronBJ, NicholsPF, PickleLW, WesleyYE, MulvihillJJ. Patterns of inheritance in hypertrophic cardiomyopathy: assessment of M-mode and two-dimensional echocardiography. Am J Cardiol1984; 53: 1087–1094
4.
BranziA, RomeoG, SpeccheiaS.Genetic heterogeneity of hypertrophic cardiomyopathy. Int J Cardiol1985; 7: 129–133
5.
GreavesSC, RocheAHG, NeutzeJM, WhitlockRML, VealeAMO. Inheritance of hypertrophic cardiomyopathy: a cross sectional and M mode echocardiographic study of 50 families. Br Heart J1987; 58: 259–266
EpsteinND, LinHJ, FananapazirL.Genetic evidence of dissociation (generational skips) of electrical from morphologic forms of hypertrophic cardiomyopathy. Am J Cardiol1990; 66: 627–631
8.
KoYL, TangTK, ChenJJ, HshiehYY, WuCW, LienWP. Idiopathic hypertrophic cardiomyopathy in identical twins. Morphological heterogeneity of the left ventricle. Chest1992; 102: 783–785
