The paper opens with a short historical survey of the evidence that the cells of tumours, including cancers, may manifest functional, secretory or other activity (œcology) of the same nature as that of the normal glandular or other cells from which they have arisen. This is followed by a short consideration of the classification and the acknowledged and doubtful endocrine or hormonic effects of primary tumours and tumour-like hyperplasias of the various endocrine glands of the body.
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