The study aims to investigate the relationship between ICU nurses’ attitudes towards caring for dying patients and self compassion.This cross-sectional study (Aug-Oct 2022) was conducted with the volunteer participation of 219 ICU nurses in Isfahan University of Medical Sciences, Iran. Data were collected through the Socio-demographic Form, the Frommelt Attitude toward Care of Dying Scale (FATCOD), and the Self-Compassion Scale (SCS).The mean score of attitude of end-of-life care and self-compassion were 92.77 ± 21.5 and 47.83 ± 7.69 respectively. A statistically significant difference was found between nurses’ education level and attitudes of end-of-life care (p < 0.001) and self-compassion. (p < 0.04) A significant difference was found between end of life care training experience and self-compassion (p < 0.03). A positive, statistically significant relationship was found between the attitudes of end-of-life care total score and self-compassion total score (p < 0.001). A significant relationship between the self-compassion and attitude toward caring for dying patients is an important finding for quality of care in ICU nurses.
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