This report describes the liver biopsy findings in an obese adolescent male suffering from benign recurrent intrahepatic cholestatic jaundice who developed transient focal feathery swelling and ground glass hepatocellular change within several weeks of indulging in glue sniffing. Clinically the situation provided a rare opportunity to observe the nature and progress of morphological features by means of sequential liver biopsies taken for the investigation of the patient's underlying jaundice. The temporal relationship between the confessed period of glue sniffing and appearance of the hepatocellular abnormality provides, in our opinion, strong supportive evidence of a definite link between the two.
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