A case of double suicide by chloroform in a pair of twins is described. At autopsy a diffuse and severe visceral congestion was noted, together with pulmonary oedema. Microscopically, an initial centrilobular liver steatosis was observed. The results of the toxicological analyses were the following: brain 50.4 ppm and 156 ppm respectively; liver 16.2 and 86.2 ppm; blood 30 ppm and 40 ppm; gastric content: chloroform absent in both cases.
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References
1.
BonnichsenR.MaehlyA. C. (1966) Poisoning by volatile compounds. II. Chlorinated aliphatic hydrocarbons. J. Forens. Sci.11, 414.
2.
BrownB. R.SipesI. G.SagalynA. M. (1974) Mechanisms of acute hepatic toxicity: chloroform, halothane and glutathione. Anesthesiol.41, 554.
3.
DefalqueR. J. (1968) The first delayed chloroform poisoning. Anesth. Analg.47, 374.
4.
GettlerA. O.BlumeH. (1931) Chloroform in brain, lungs and liver: quantitative recovery and determination. Arch. Pathol.11, 554 (quoted by Bonnichsen and Maehly).
5.
PoobalasinghamN.PayneJ. P. (1978) The uptake and elimination of chloroform in man. Br. J. Anaesth.50, 325.
6.
SchroederH. G. (1965) Acute delayed chloroform poisoning: a case report. Br. J. Anaesth.37, 972.
7.
StormsW. W. (1973) Chloroform parties. J. Am. Med. Ass.225, 160.
8.
TimmsR. M.MoserK. M. (1975) Toxicity secondary to intravenously administered chloroform in humans. Arch. Intern. Med.135, 1601.
9.
von MeyerL.HauckG. (1972) Zum gaschroma-tographischen Nachweis einiger als Rauschmittel benutzen Chlorkohlenwasserstoffe mit Elektronen-einfangdetektor (ECD). Beitr. gerichtl. Med.29, 408.