The recognition of serum protein alterations in disease has firmly established the value of electrophoresis in laboratory diagnosis during life. The diagnostic role of postmortem serum protein electrophoresis has not become so readily established because of the lack of definitive data pertaining to the limits of serum protein change which occur following death and the difficulties inherent in obtaining such data.
Get full access to this article
View all access options for this article.
References
1.
BenekeG. (1959) “Zur Frage de Verwendbarkeit von Leichenseren zur papierelektrophorese.” (Experimentelle Untersuchungen an der Ratte.)Zbl. Allg. Path. Path. Anat.99, 389.
2.
BenekeG. (1960) “Uber die Ursachen der postmortalen Veränderungen des Serumpherogrammes.” (Experimentelle Untersuchungen an der Ratte). Z. Ges Inn. Med.15, 323.
3.
BenekeG.BahnK. (1961) “Veränderungen des Serumund Liquorpherogrammes menschlicher Leichen in Abhängigkeit vonder Zeit nach dem Tode.”Z. Ges. Inn. Med.16, 232.
4.
DunnW. L.PearceR. H. (1961) “The clinical value of paper electrophoresis.”Canad. Med. Ass. J.84, 272.
5.
FisherB. (1953) “Recent contributions of electrophoresis to clinical pathology.”Amer. J. clin. Path.23, 246.
6.
LongsworthL. G.ShedlovskyT.MacInnesD. A. (1939) “Electrophoretic patterns of normal and pathological human blood serum and plasma.”J. Exp. Med.70, 399.
7.
NealeF. C.AberG. M.NorthamB. E. (1958) “The demonstration of intravascular hemolysis by means of serum paper electrophoresis and a modification of Schumm's reaction.”J. clin. Path.11, 206.
8.
RobinsonD. M.KellenbergerR. E. (1962) “Comparison of electrophoretic analyses of antemortem and postmortem serums.”Amer. J. clin. Path.38, 371.
9.
SchlangH. A.DavisD. R. (1958) “Paper electrophoretic studies of postmortem serum proteins.”Amer. J. med. Sci.236, 472.
10.
SchleyerF. (1954) “Papierelectrophoretische Untersuchungen des Eiweissbildes von Leichenseren.”Arch. exper. Path. u. Pharmakol.221, 306.
11.
SchreinerG. E.MaherJ. E. (1961) Uremia: Biochemistry, Pathogenesis and Treatment.Springfield, Ill.: C. C. Thomas, pp. 204–207.
12.
SeibertF. B.NelsonJ. W. (1943) “Electrophoresis of serum. Serum proteins in tuberculosis and other chronic diseases.”Amer. Rev. Tuberc.47, 66.
13.
SeibertF. B.SeibertF. V.AtnoA. J.CampbellH. W. (1947) “Variation in protein and polysaccharide content of sera in the chronic diseases, tuberculosis, sarcoidosis and carcinoma. J. clin. Invest.26, 90.
14.
ShedlovskyT.ScudderJ. (1942) “A comparison of erythrocyte sedimentation rate and electrophoretic patterns of normal and pathological human blood.”J. Exp. Med.75, 119.
15.
SpainD. M.BradessV. A.GreenblattI. J. (1956) “Gamma globulin deficiency in infancy. Ann. N. Y. Acad. Sci.66, 176.
16.
WiemeR. J. (1959) Studies on Agar Gel Electrophoresis. Brussels; Arscia Uitgaven N.V., pp. 87, 303.